Guinea will be proceeding to quarter finals after beating Equatorial Guinea 1-0 in a regrettable match which saw Guinea scoring at the last minute of the added time.
The game was set to head to extra time when striker Bayo stooped to guide Ibrahim Diakite’s cross from the right flank just inside the near post.
Guinea have made it to the last eight for the first time since 2015 and will meet on Friday with either DRC Congo or Egypt in the quarter-finals.
The Le Havre striker’s header, clocked at 97 minutes and 38 seconds, is the latest winning goal in a knockout match in the history of the Africa Cup of Nations.
Nsue blasted a volley over the bar from 12 yards two minutes after the restart, but the complexion of the game changed when Bikoro was shown a straight red after following through with a clearance in midfield and catching Bayo with some force.
Equatorial Guinea were handed a glorious chance to take the lead when the video assistant referee sent Omar Artan to his touchline screen, and the referee awarded a penalty, deciding Sylla had caught Iban Salvador on the back of the leg after the midfielder had controlled a pass.
Veteran 34-year-old striker Nsue, who plays in the third tier in Spain, could however not add to his tally at the finals despite sending Guinea keeper Ibrahim Kone the wrong way.
Equatorial Guinea had reached at least the quarter-finals on their previous three appearances at Afcon.